People at the Centre
The Comprehensive Cancer Imaging Centre relies for its success on the wide range of expertise present in the associated researchers. There are 33 Principle and Co-Investigators, the Centre directly employs over 30 researchers, students and support staff, and there are a great many collaborators working with us in all aspects of the Centre.
Centre Staff
Principle and Co-Investigators |
Researchers and Support Staff |
Dr Simon Ameer-Beg Dr Margaret Ashcroft Professor Paul Beard Professor Richard Begent Professor Phil Blower Professor Chris Boshoff Professor Kerry Chester Professor Ton Coolen Dr Michael Douek Professor Peter Ell Dr Paul Ellis Dr Adam Gibson Dr Alan Green Dr Helen Hailes Professor Steve Halligan Professor Dave Hawkes Professor Brian Hutton Dr David Landau Dr Mark Lythgoe Professor Paul Marsden Dr Tim Meyer Dr Greg Mullen Professor Tony Ng Dr Mike O’Doherty Professor Quentin Pankhurst Professor Barbara Pedley Professor Sarah Pinder Professor Arnie Purushotham Professor Michele Saunders Professor Tobias Schaeffter Dr Susan Short Dr James Spicer Dr Alethea Tabor Professor Tarek Yousry |
Dr Maggie Cooper Dr Louise Enfield Dr Kjell Erlandsson Dr Gilbert Fruhwirth Dr Christina Gewinner Mr Richard Hocking Dr Yan Jiao Dr Jan Laufer Dr Katherine Lawler Ms Cristina Naceur Lombardelli Dr Jamie McClelland Dr Nick Mitchell Dr Simon Poland Dr Vin Rajkumar Dr Arunabha Roy Dr Debashis Sarker Dr Karen Shaw Dr Simon Walker-Samuel Dr Amanda Weeks Ms Natalie Woodman |
Dr Simon Ameer-Beg
Randall Division of Cell & Molecular Biophysics
King’s College London
http://www.kcl.ac.uk/schools/biohealth/research/randall/res-sections/cellimaging/
Short Biography
BSc. (Hons) Laser and Laser Physics, University Of Essex,1993.
MSc. Physics of Laser Communications, University Of Essex, 1994.
PhD (Physics/Chemistry), University of Central Lancashire, 1999.
Post Doctoral Researcher: Gray Cancer Institute, 2000-2006.
Non-Clinical Lecturer: King’s College London, 2006 onwards.
Selected References
Calleja V., Ameer-Beg S.M., Vojnovic B., Woscholski R., Downward J., Larijani B. (2003). Monitoring conformational changes of PKB/AKT by fluorescence lifetime imaging in intact cells. Biochem. J. 372, pp33.
Kysela B., Doherty A.J., Chovanec M., Ameer-Beg S.M., Vojnovic B., Girard P.-M. and Jeggo P.A. (2003). Ku stimulation of DNA ligaseIV-dependent ligation requires inward movement along the DNA molecule. J. Biol. Chem., 278, pp22466.
Barber P.R., Vojnovic B., Ameer-Beg S.M., Hodgkiss R.J., Tozer G.M. and Wilson J. (2003). Semi- Automated Software for the 3D Delineation of Complex Vascular Networks. J. Microscopy, 211, p54.
Ameer-Beg S.M., Ormson S., Poteau, X, Brown R.G., Foggi P., Bussotti L. and Neuwahl F.V.R. (2004). Ultrafast measurements of charge and excited state intramolecular proton transfer in solutions of 4’-N,N-dimethyl-amino-derivatives of 3-hydroxyflavone. J. Phys. Chem. A 108(34), pp6938-6943.
Jumah N.A., Ameer-Beg S.M., White N., Prasad K.V.R., Bellhouse B.J. (2004). Identification of second harmonic optical effects from vaccine coated gold micro-particles. Phys. Med. Biol. 49(16) pp3603
Tozer G. M., Ameer-Beg S. M., Baker J., Barber P. R., Hill S. A., Hodgkiss R. J., Locke R., Prise V. E., Wilson I. and Vojnovic B. (2005) Intravital Imaging of Tumour Vascular Networks using Multiphoton Fluorescence Microscopy, Advanced Drug Delivery Reviews 57(1), pp135
Errington, R.J., Ameer-beg, S.M., Vojnovic, B., Patterson, L.H., Zloh, M. and Smith P.J. (2005). Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells. Advanced Drug Delivery Reviews 57(1), pp153
Peter M. *, Ameer-Beg S. M.*, Hughes M.K.Y., Keppler M.D., Prag S., Marsh M., Vojnovic B., Ng T. (2005). Multiphoton-FLIM quantification of the EGFP- mRFP1 FRET pair for localization of membrane receptor-kinase interactions. Biophys. J. 88(2), pp1224.
Parsons M.*, Monypenny J.*, Ameer-Beg S.M.*, Millard T.H., Machesky L.M, Peter M., Keppler M.D., Schiavo G., Watson R., Chernoff J., Zicha D., Vojnovic B., Ng T.C. (2005). Spatially distinct activation of PAK1 and N-WASP by Cdc42 in breast carcinoma cells. Mol. Cell. Bio. 25, pp1680.
- R. Matthews, H. D. Summers, K. Njoh, R. J. Errington, P. J. Smith, P. Barber, S. Ameer-Beg, and B. Vojnovic (2006). Technique for measurement of fluorescence lifetime by use of stroboscopic excitation and continuous-wave detection, Applied Optics 45, pp2115
Ganesan S., Ameer-beg, S. M., Ng, T. T. C., Vojnovic B., Wouters F. S. (2006) A dark YFP-based Resonance Energy Accepting Chromoprotein (REACh) for FRET with GFP. PNAS 103(11), pp4089.
Njoh, K., Patterson, L.H.., Zloh, M., Wiltshire, M., Fisher, J., Ameer-Beg, S.M., Bai, Y., Matthews, D.R., Errington, R.J., and Smith P.J., (2006). Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells, Cytometry A, 69A, pp-805.
McConnell, G., Girkin, J.M., Ameer-Beg, S.M., Barber, P.R., Vojnovic, B., Ng, T., Banerjee, A., Watson, T.F., Cook, R.J. (2007) Time-correlated single-photon counting fluorescence lifetime confocal imaging of decayed and sound dental structures with a white-light supercontinuum source, J. Microscopy, 225(2), p126.
Prag, S., Parsons, M., Keppler, M.D., Ameer-beg, S.M., Hunt, J., Barber, P., Beavil, A.J., Calvert, R., Arpin, M., Vojnovic, B. and Ng, T.(2007) Ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and downstream activation of Cdc42. Mol Biol Cell, 18, pp2935.
Reyes-Aldasoro, C.C., Wilson, I., Prise, V. E., Barber, P. R., Ameer-Beg, S. M., Vojnovic, B., Cunningham, V. J., and Tozer, G. M. (2007) Estimation of Apparent Tumor Vascular Permeability from Multiphoton
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Dr Margaret Ashcroft
Department of Metabolism and Experimental Therapeutics
Division of Medicine
UCL
m.ashcroft(at)ucl.ac.uk
http://www.ucl.ac.uk/medicine/cell-signalling
Short Biography
Reader in Cancer Biology
Selected References
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Professor Paul Beard
Department of Medical Physics and Bioengineering
UCL
pbeard(at)medphys.ucl.ac.uk
http://www.ucl.ac.uk/medphys/